I’ve searched your archive in vain–how is it that the vital 6eld of phytoestrogen research has escaped your scrutiny? The straight dope, please: Can herbal supplements containing phytoestrogen truly increase a woman’s breast size significantly? Is this method safe, or are there negative side effects (sure they’re bigger, but they feel like baseballs)? You know you’re the only source I trust. –Impatient, via e-mail

Best of Chicago voting is live now. Vote for your favorites »

For those who don’t know phyto from fiduciary, a little theory: Phytoestrogens are chemicals found in plants that mimic the female sex hormone estrogen. Female sex hormones give rise to female secondary sex characteristics, e.g., the enlargement (sometimes to an impressive degree) of the milk-producing glands whence the class Mammalia derives its name. Ergo, some would reason, phytoestrogens = more hormones = bigger tits.

But probably not by much. The main phytoestrogen in soybeans, genistein, for instance, is only 0.1 percent as strong as the human-produced variety. For women who do produce enough estrogen of their own, phytoestrogens actually decrease overall estrogen activity by competing with the homegrown estrogen for positions on estrogen receptor sites; when phytoestrogens latch onto these sites, they push aside the real estrogen and provide only a weaker version. In fact, that could be their real benefit, some experts think–by lowering the body’s effective estrogen level, phytoestrogens may reduce a woman’s chance of developing breast cancer. But here’s the thing: if so, they’d likely make breasts smaller, not larger.